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. Author manuscript; available in PMC: 2010 May 13.
Published in final edited form as: Brain Res. 2009 Feb 27;1270:107–111. doi: 10.1016/j.brainres.2009.02.034

Figure 1.

Figure 1

Quantification of the protein expression of Ca2+-activated K+ channels. Representative immunoblots of BK, SK1, SK2 and SK3 subtypes of Ca2+-activated K+ channels obtained from IC neurons of control SD rats, SN-GEPR-3s and SE-GEPR-3s are showed in insets. The levels of protein expression of SK1 and SK3 subtypes of Ca2+-activated K+ channels were significantly decreased in IC neurons of SN-GEPR-3s compared to control SD rats. In contrast, the levels of proteins associated with SK2 channels were significantly increased in IC neurons SN-GEPR-3s compared to control SD rats. Seizure episodes slightly increased the protein expression of SK1 and SK2 channels in IC neurons compared to SN-GEPR-3s, but did not alter expression of SK3 channels. The levels of protein expression of BK channels were slightly reduced in SN-GEPR-3s compared to control SD rats as well as in SE-GEPR-3s compared to SN-GEPR-3s. Each column represents the mean ± S.E.M. (n = 8). *P <0.05 (ANOVA followed by post hoc test).