Table 1.

Effect of KB-R7943 and LIGA-20 on transient increase of [Ca²⁺]_ne/er following Ca²⁺ application

	Control	KB-R7943	LIGA-20
		Mean ± SEM (n)
NG108–15 (Undifferentiated )	0.265 ± 0.020 (33)**	NA	0.440 ± 0.013 (31)*
NG108–15 (Differentiated)	0.452 ± 0.028 (43)	0.155 ± 0.015 (38)*	NA
NG-CR72	0.191 ± 0.040 (30)	0.095 ± 0.020 (36)*	0.292 ± 0.030 (31)*
C6	0.443 ± 0.110 (32)	0.049 ± 0.04 (32)*	NA
Jurkat	0.020 ± 0.024 (31)	0.004 ± 0.005(31)	NA

[Ca²⁺]_ne/er measurement was performed as in Figs. 3 and 5, and transient increase after application of extrinsic Ca²⁺ was calculated. Data are mean elevation of R_535/480 ± SEM. Figures in parentheses indicate number of cells employed. NA, not assayed. Statistical difference was analyzed with 2-tailed Student's t-test;

*, P < 0.001 vs. control;

**, P < 0.001 vs. differentiated NG108–15 cells.