Skip to main content
. Author manuscript; available in PMC: 2010 Jun 12.
Published in final edited form as: Mol Cell. 2009 Jun 12;34(5):545–555. doi: 10.1016/j.molcel.2009.04.018

Figure 3. Simulations of transcriptional interference cannot explain experimental observations using existing mechanisms.

Figure 3

(A) Schematic of different mechanisms of transcriptional interference, in which the left (darker) promoter is interfering with the right (lighter) promoter.

(B) Alignment of experimental measurements of promoter activity with the existing mathematical model of TI. Points are experimental data and lines are the results of stochastic simulations of TI, incorporating the mechanisms of occlusion, ‘sitting duck’, and collisions.