Table 9.

Biological process analysis of nonsense-mediated mRNA decay candidates.

	Human			Mouse
Biological process terms	All genes	NMD genes	P value	All genes	NMD genes	P value
Biological process unclassified	6,172	327O	1.45 × 10-11	6080	244O	1.28 × 10-11
Developmental processes	1,908	43U	1.68 × 10-3	1867	32U	5.70 × 10-2
Cell-surface receptor-mediated signal transduction	1,513	30U	3.56 × 10-3	-	-	-
Sensory perception	465	5U	1.08 × 10-2	971	13U	7.10 × 10-2
Signal transduction	3,127	87U	1.44 × 10-2	3491	66U	8.75 × 10-3
Chemosensory perception	203	0	6.03 × 10-2	545	2U	5.14 × 10-3
Olfaction	-	-	-	539	2U	8.14 × 10-3
Total number of genes	18,172	693		17939	491

Notes. NMD = nonsense-mediated mRNA decay. The biological processes with Bonferroni-corrected P values < 0.1 are listed; the complete result is presented in Additional file 3. ^O: biological process was over-represented in NMD candidates; ^U: biological process was under-represented in NMD candidates; symbol '-' indicates that the biological process exhibited a P value > 0.1 in this species, but not in the other species.