Table 2.
Sites of phosphorylation for CaMKII on GABAA receptor β and γ2 subunits
| Receptor subunit | CaMKII substrate residues | Reference | ||
|---|---|---|---|---|
| α1 | n/i | — | — | Churn et al. 2002 |
| β1 | S384 | S409 | — | McDonald & Moss, 1994 |
| β2 | — | S410 | — | |
| β3 | S383 | S409 | — | |
| γ2S | — | S348 | T350 | Houston et al. 2007 |
| γ2L | S343 | S348 | T350 | |
The sites of CaMKII phosphorylation on GABAA receptor subunits are shown. The residues (S-serine; T-threonine) are located between the 3rd and 4th transmembrane domains of β and γ2 subunits and have been identified using biochemical analyses of GSK fusion proteins. n/i- residue(s) not identified.