Fig. 3.

Antibody responses to Plasmodium falciparum isolate A4U amongst children presenting to hospital with P. falciparum malaria and during follow-up. Shown are the median plus interquartile range of the log transformed mean fluorescence intensity (MFI) for responses to A4U amongst 39 children (mean age 29.5 months) resident in Kilifi District from sera taken at acute presentation (acute) and then at 1, 2, 3 and 6 weeks follow-up. The median and interquartile ranges of the log transformed MFI from asymptomatic parasite-positive children (mean age 29.01 months) and parasite-negative children (mean age 28.96 months) from the same area are shown for comparison. The horizontal line represents the log transformed MFI obtained from 20 non-malaria-exposed UK donors plus 3 SD.