Table 1.
Characteristics of five hyaluronans
| Product | Origin (method of production) | Molecular weight (kd) | Amount per injection (ml) | Active ingredients per injection | Number of injections per cycle |
|---|---|---|---|---|---|
| Hylagan | Rooster combs (naturally derived) | 500–730 | 2 | 20 mg sodium hyaluronate | 3 or 5 weekly |
| Supartz | Rooster combs (naturally derived) | 620–1170 | 2.5 | 25 mg sodium hyaluronate | 5 weekly |
| Orthovisc | Rooster combs (naturally derived) | 1000–2900 | 2 | 30 mg sodium hyaluronate | 3 or 4 weekly |
| Synvisc | Rooster combs (chemically modified or cross-linked) | 80%: 6000; 20%: >6000 | 2 | 16 mg sodium hyaluronate derivative | 3 weekly |
| Euflexxa | Bacterial fermentation (naturally derived) | 2600–3400 | 2 | 20 mg sodium hyaluronate | 3 weekly |