Table 3.

Caki-1 Cells Induced Elimination of CD56⁺CD16⁺ Cell Subset Is Caspase-Independent^*.

Experiments	Caki-1 Cells
	-	-	+	+
	-	Z-VAD (40 µM)	-	Z-VAD (40 µM)
1	12.5	8.0	0.91	1.08
2	5.0	3.91	0.95	0.93
3	9.4	9.28	2.32	3.05
Mean ± SD†	8.96 ± 3.7	7.0 ± 2.8	1.39 ± 0.8	1.68 ± 1.1

^*Peripheral blood mononuclear cells were cultured in the presence of IL-2 with or without Z-VAD-FMK as detailed in the Materials and Methods section before culture in the presence or absence of Caki-1 RCC cells.

^†t test: CD56⁺CD16⁺ cells versus CD56⁺CD16⁺ cells + Z-VAD-FMK, P = .52; CD56⁺CD16⁺ cells + Caki-1 cells versus CD56⁺CD16⁺ cells + Caki-1 cells + Z-VAD-FMK, P = .740; CD56⁺CD16⁺ cells versus CD56⁺CD16⁺ cells + Caki-1 cells, P = .02; CD56⁺CD16⁺ cells versus CD56⁺CD16⁺ cells versus CD56⁺CD16⁺ cells + Caki-1 cells + Z-VAD-FMK, P = .03.