(A, B) Macroscopic images of lung tumors from a 9-month-old SPC-IGFIR transgenic mouse. Hematoxylin and eosin-stained lung sections from a CCSP-IGFIR transgenicmouse (C, E) and an SPC-IGFIR transgenic mouse (D, F). Scale bars, 800 µm (C, D) and 100 µm (E, F).