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Repression of transcription from the MDR1 gene promoter after p53 repair. Calu-6 cells were cotransfected with the MDR-luc reporter construct and an empty vector or each ribozyme expression vector (pRib41p53 or pRib65p53). Relative luciferase activity was quantitated as a percentage of the vector control sample, and average values ± SD for luciferase activity from three independent experiments are shown.
