Table 1.
Strain-Differences in Blood Pressure, Body Weight and Survival among S and Congenic Rat Strains.
Strain | BP, week 3, mm Hg |
BP, week 4, mm Hg |
Body weight, initial, g |
Days Survived on 4% NaCl diet |
---|---|---|---|---|
S | 173.5 ± 4.0 [15] | 181.9 ± 4.1 [15] | 161.0 ± 2.1 [20] | 64.8 ± 6.4 [21] |
RNO3 | 154.7 ± 1.7 [15] | 160.5 ± 2.3 [15] | 145.1 ± 3.6 [15] | 96.9 ± 7.1 [15] |
RNO3 + RNO7 | 152.7 ± 2.6 [16] | 157.8 ± 3.2 [16] | 150.2 ± 3.4 [20] | 126.4 ± 8.5 [20] |
RNO7 | 160.5 ± 3.0 [14] | 170.8 ± 3.3 [14] | 150.2 ± 2.5 [19] | 72.5 ± 6.8 [19] |
P (overall) | <0.0001 | <0 .0001 | <0.0001 | 0.002 |
P (S vs. RNO3) | 0.002 | 0.001 | 0.002 | 0.002 |
P (S vs. RNO3 + RNO7) | 0.001 | 0.0004 | 0.015 | <0.0001 |
P (S vs. RNO7) | NS, 0.067 | 0.052 | 0.004 | NS |
P (RNO3 vs. RNO3 + RNO7) |
NS | NS | NS | 0.016 |
P (RNO3 vs. RNO7) | NS | 0.018 | NS | 0.009 |
P (RNO7 vs. RNO3 + RNO7) | NS | 0.013 | NS | <0.0001 |
BW was measured on 40-42 day-old Experiment 1 rats. Tail-cuff BP was measured during the third (days 17 and 18) and fourth weeks (days 26 and 27) on a 2% NaCl diet. After BP measurement, rats were maintained on a 4% NaCl diet until they died or became moribund. Numbers of rats per strain measured for each trait are in brackets. NS, not significant (P>0.05).