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. Author manuscript; available in PMC: 2009 Jun 17.
Published in final edited form as: J Struct Biol. 2008 Mar 31;162(3):404–410. doi: 10.1016/j.jsb.2008.02.010

Figure 5.

Figure 5

AFM images associating topographic variations (solid red lines) with indentation elastic modulus values (broken red lines) along black dashed lines on isolated collagen fibrils with varying appearance. A. recombinant collagen fibril without mineral had gap-overlap height differences of 5 nm. Modulus values varied from about 30 MPa at gaps to 60 MPa at the overlaps. B. Fully demineralized human dentin collagen fibrils showing gap overlap height differences of about 6 nm and modulus variations between 10 MPa at gaps to 40 MPa in the overlap zones. C. Dentin collagen fibril after 240 s demineralization showing sinusoidal periodic variations in topography with gap-overlap height differences of 2–3 nm. Modulus values at the gaps were 200–400 MPa and at the overlaps were 500–800 MPa. D. Smooth dentin collagen fibril showing minimal gap-overlap height differences and modulus variations between 1.2 and 1.5 GPa.