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. Author manuscript; available in PMC: 2009 Jun 17.
Published in final edited form as: Exp Eye Res. 2007 Oct 2;86(1):81–91. doi: 10.1016/j.exer.2007.09.011

Figure 4. The exon-intron organization of human Kir7.1 gene (KCNJ13).

Figure 4

(A) The exon-intron organization of human Kir7.1 gene determined by comparing a published human genomic DNA sequence (GenBank accession no. AC064852), the Kir7.1 (GenBank accession no. AY758241) and Kir7.1S (GenBank accession no. AY758240) cDNA sequences revealed in this study, and a published Kir7.1 cDNA sequence (GenBank accession no. NM_002242) using Lasergene software (DNASTAR) and information obtained from AceView (www.humangenes.org). Diagonal lines indicate introns and boxes represent exons. The novel alternative donor splice site is located within the second exon. (B) Alignment of consensus sequences of splice sites with Kir7.1 and Kir7.1S sequences. Bold lowercase letters indicate GT and AG base pairs for donor and acceptor sites. M represents A or C; r represents a or g.