Figure 4.

The effects of neomycin (1–4 mmol·L⁻¹) on the slow wave activity of the guinea pig prostate (A) are depicted in an expanded time scale (B). Neomycin (1 mmol·L⁻¹) depolarized the resting membrane potential and reduced the half-amplitude duration of the transient depolarization (Bb). At a higher concentration (4 mmol·L⁻¹), neomycin lead to a further depolarization of the membrane potential and abolished slow wave activity (Bc). The broken horizontal line indicates 0 mV.