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. 2009 Feb 2;156(4):545–562. doi: 10.1111/j.1476-5381.2009.00052.x

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© 2009 The Authors. Journal compilation © 2009 The British Pharmacological Society

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Endothelial vasoactive factors and smooth muscle BK_Ca activity. 20-HETE, 20-hydroxyeicosatetraenoic acid; BK_Ca, calcium-activated potassium channels of large conductance; cAMP, cyclic-adenosine monophosphate; cGMP, cyclic-guanosine monophosphate; COX, cyclooxygenase; EC, endothelial cell; EDCFs, endothelium-derived contracting factors; EDRFs, endothelium-derived relaxing factors; EETs, epoxyeicosatrienoic acids; eNOS, endothelial nitric oxide synthase; GS, G-protein S; GSα, α subunit of G-protein S; H₂O₂, hydrogen peroxide; IP, prostcyclin receptor; NO, nitric oxide; NOX, NADPH oxidase; P450 2C-2J or 4A, cytochrome P450 monooxygenase 2C, 2J or 4A; PGI₂, prostacyclin; R?, putative receptor; ROS, reactive oxygen species; sGC, soluble guanylate cyclase; SOD, superoxide dismutase; TP, thromboxane/endoperoxide receptor; TRPV4, vanilloid transient receptor potential channel 4; VSMC, vascular smooth muscle cell; XO, xanthine oxidase.