Figure 5.

Potassium currents in porcine coronary arterial endothelial cells. Effect of the combination of different inhibitors of potassium channels in freshly isolated porcine coronary arterial endothelial cells (whole cell configuration of the patch-clamp technique). (A) Representative K⁺-currents elicited by 10 mV voltage steps in control, after application of iberiotoxin (IbTX), iberiotoxin + apamin (IbTX + Apamin) and iberiotoxin + apamin + charybdotoxin (IbTX + Apamin + ChTX). (B) Summary bar graph: the presence of apamin (Apa.) and charybdotoxin produced a statistically significant inhibition of the amplitude of the K⁺-currents.