Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2009 Feb 18;156(6):994–1008. doi: 10.1111/j.1476-5381.2008.00110.x

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Journal compilation © 2009 The British Pharmacological Society

PMC Copyright notice

Effects of carisbamate (CRS) upon excitatory synaptic transmission. CRS (100–400 µmol·L⁻¹) produced a selective, concentration-dependent suppression of depolarizing postsynaptic potentials (DPSPs) evoked by subthreshold lateral olfactory tract (layer Ia, LIa)-afferent fibre stimulation. (A) Superimposed subthreshold LIa DPSPs are elicited in control conditions and in CRS (100 and 250 µmol·L⁻¹ as indicated). (B) Pooled log–concentration response curve showing the inhibitory effect of CRS upon LIa DPSP amplitude, expressed as percentage of control (data points are means ± SEM, n= 6; best-line fit gave EC₅₀= 118 µmol·L⁻¹; data points significantly different from control are indicated by *, P < 0.05).