Figure 2.

Effects of chelerythrine application in vitro on the chloride channel conductance (gCl) of extensor digitorum longus muscle of fluvastatin (5 mg·kg⁻¹ or 20 mg·kg⁻¹), atorvastatin (10 mg·kg⁻¹) and fenofibrate (60 mg·kg⁻¹)-treated and control (CTRL) rats. Each bar represents the mean ± SEM of gCl measured in muscle fibres in the presence of chelerythrine (1 µmol·L⁻¹) with respect to the value recorded in the absence of the compound (physiological solution). The means have been calculated from 25–35 fibres of 3–5 rats. *Significantly different with respect to the value measured in the absence of chelerythrine (by Student's t-test) (P < 0.05 or less). #Significantly different with respect to control value measured in physiological solution (by Student's t-test) (P < 0.001).