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Comparison of the β2-adrenoceptor-mediated effects of (−)-adrenaline in the presence of CGP20712A (CGP) and the inhibition of both PDE3 and PDE4 in four cardiac regions. Antagonism by ICI118551 (ICI). (A) Sinoatrial tachycardia. (B) Positive inotropic effects on left atrium. (C) Positive inotropic effects on free right ventricular wall. (D) Positive inotropic effects on left ventricular papillary muscle. For further details see Figure 1. Cil, cilostamide; Rol, rolipram.
