Table 1.

Binding affinities of A-940894 and JNJ7777120 at recombinant human or rat histamine H₁, H₂, H₃ and H₄ receptors

Receptor subtype	Ki (nmol·L−1)
	A-940894	JNJ7777120
Human H4	71a	12
	(26–196)b	(2–63)
Rat H4	7.6	3.1
	(5.1–11.4)	(1.6–6.0)
Human H1	>5000	2767
		(1087–7048)
Human H2	>5000	>5000
Human H3	3899	2210
	(2582–5902)	(1696–2882)
Rat H3	483	1382
	(333–702)	(1083–1764)

^an≥ 3.

^b95% confidence interval.