Table 2.

Functional properties of A-940894 and JNJ7777120

Receptor and assay	Kb (nmol·L−1)
	A-940894	JNJ7777120
Human H4– FLIPR	74a	4.7
	(60–92)b	(4.4–5.0)
Rat H4– FLIPR	15	2.8
	(10–22)	(2.6–3.1)
Mouse H4– FLIPR	18	2.7
	(15–23)	(2.0–3.5)
Rat H4– GTPγS	60	66
	(32–112)	(64–68)
Mouse mast cells – shape change	316	594
	(210–476)	(336–1054)

^an≥ 3.

^b95% confidence interval.

FLIPR, fluorometric imaging plate reader.