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. 2009 May;157(1):44–54. doi: 10.1111/j.1476-5381.2009.00236.x

Table 2.

Functional properties of A-940894 and JNJ7777120

Receptor and assay Kb (nmol·L−1)
A-940894 JNJ7777120
Human H4– FLIPR 74a 4.7
(60–92)b (4.4–5.0)
Rat H4– FLIPR 15 2.8
(10–22) (2.6–3.1)
Mouse H4– FLIPR 18 2.7
(15–23) (2.0–3.5)
Rat H4– GTPγS 60 66
(32–112) (64–68)
Mouse mast cells – shape change 316 594
(210–476) (336–1054)
a

n≥ 3.

b

95% confidence interval.

FLIPR, fluorometric imaging plate reader.