. 2009 Mar 26;157(2):320–330. doi: 10.1111/j.1476-5381.2009.00156.x

Table 1.

Binding affinity of benzylidine-anabaseine analogues for the Torpedo nAChR agonist-binding sites

Benzylidine-anabaseine analogue	K_i^a(µmol·L⁻¹⁾	n_H^b
DMXBA	10.6 ± 0.8	1.27 ± 0.11
4OH-DMXBA	2.7 ± 0.2	1.07 ± 0.06

Data shown are the means ± SD, from two to three experiments each performed in triplicate.

Inhibition constants were calculated from Figure 3 using eq. 2.

Hill coefficients.

4OH-DMXBA, 3-(4-hydroxy-2-methoxybenzylidene)-anabaseine; DMXBA (or GTS-21), 3-(2,4-dimethoxybenzylidene)-anabaseine; nAChR, nicotinic acetylcholine receptor.