Table 1.

General characteristics of sorafenib-treated and-untreated rats (means ± SEM, five sham-operated rats, seven BDL rats)

	Body weight (g)	Liver weight (g)	Spleen weight (g)	Gastrointestinal tract weight (g)
Sham	332 ± 6.6	10.2 ± 0.48	0.57 ± 0.02	11.3 ± 1.12
Sham + sorafenib	295 ± 3.7#	11.5 ± 0.21	0.57 ± 0.04	12.8 ± 0.475
BDL	333 ± 19.2	19.4 ± 2.73#	1.84 ± 0.19#	13.4 ± 1.07
BDL + sorafenib	289 ± 10.4	15.5 ± 1.34	1.34 ± 0.10†	11.6 ± 1.05

^#P < 0.05 versus sham

^†P < 0.05 versus BDL.

BDL, bile duct ligation.