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. Author manuscript; available in PMC: 2009 Nov 1.
Published in final edited form as: Clin Cancer Res. 2008 Nov 1;14(21):6744–6750. doi: 10.1158/1078-0432.CCR-08-1032

Figure 2. The effect of caspase 9 on gemcitabine-mediated radiosensitization.

Figure 2

Wild type or caspase 9 dominant negative (DN) MCF-7 cells were exposed to equicytotoxic concentrations of gemcitabine for 24 hours prior to treatment with 0 − 8 Gy radiation. Survival was determined by a clonogenic survival assay as previously described (91). Data are expressed as the radiation enhancement ratio which was calculated as the ratio of the mean inactivation dose for drug treated cells to non-drug treated cells (ER = 1). Data are from the mean of 3 independent experiments ± standard error.