Figure 2.

Vimentin-positive cells in wild-type and W/W^v bladder. Vimentin-positive cells in whole-mount preparations of wild-type (a,b) and W/W^v (c,d) mouse detrusor. Vimentin (intermediate) filaments are found in interstitial cells of Cajal (ICC) and fibroblasts but not in smooth muscle cells and vimentin antibodies are often used to label ICC. Vimentin-positive cells had several morphologies including rounded, stellate or elongated cell bodies with branched processes and are likely to include both ICC and fibroblasts. All images are projections of a stack of optical sections captured with a confocal microscope.