Table 4.
Unadjusted |
Adjusted |
|||||
---|---|---|---|---|---|---|
Overall | HBPrx vs. NBP* | HBP vs.NBP* | Overall | HBPrx vs. NBP* | HBP vs. NBP* | |
Baseline capillary density | ||||||
Mean difference (95%CI) | −2.9 (−9.1, 3.3) | 3.4 (−3.7, 10.5) | −3.7 (−10.3, 2.9) | 4.3 (−3.1, 11.8) | ||
p | 0.320 | 0.353 | 0.351 | 0.438 | 0.268 | 0.254 |
Postocclusive reactive hyperemia capillary density | ||||||
Mean difference (95%CI) | −8.4 (−15.1, −1.6) | −0.91 (−8.7, 6.9) | −8.4 (−15.6, −1.2) | 0.57 (−7.6, 8.8) | ||
p | 0.051 | 0.016 | 0.817 | 0.160 | 0.023 | 0.891 |
Venous occlusion (maximal) capillary density | ||||||
Mean difference (95%CI) | −1.3 (−8.6, 6.0) | 5.8 (−2.7, 14.2) | −2.3 (−10.1, 5.5) | 5.6 (−3.2, 14.5) | ||
p | 0.316 | 0.726 | 0.178 | 0.527 | 0.568 | 0.211 |
% Capillary recruitment | ||||||
Mean difference (95%CI) | −7.0 (−9.5, −4.5) | −6.6 (−9.4, −3.7) | −5.7 (−8.4, −3.1) | −5.7 (−8.7, −2.7) | ||
p | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
% Perfused capillaries | ||||||
Mean difference (95%CI) | −9.9 (−12.4, −7.4) | −8.6 (−11.5, −5.7) | −8.7 (−11.2, −6.2) | −6.5 (−9.3, −3.6) | ||
p | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
Endothelial function: FBFmax/FBFbase | ||||||
Mean difference (95%CI) | −3.2 (−4.3, −2.1) | −2.3 (−3.6, −1.0) | −2.5 (−3.6, −1.3) | −1.8 (−3.1, −0.6) | ||
p | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
Microvascular structure: FVRmax | ||||||
Mean difference (95%CI) | 2.6 (1.6, 3.6) | 1.5 (0.3, 2.6) | 2.0 (1.0, 3.0) | 1.3 (0.2, 2.5) | ||
p | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
NBP: normal blood pressure; HBPrx: high blood pressure, treated; HBP: high blood pressure, untreated.