Table 2.
Overall survival of hepatocellular carcinoma patients after liver transplantation based on preoperative variables
Parameters | n |
Survival, % |
P-value | ||
---|---|---|---|---|---|
1 year | 3 years | 5 years | |||
Gender | |||||
Male | 155 | 82.6 | 74.2 | 61.9 | 0.3072 |
Female | 31 | 90.0 | 83.3 | 64.0 | |
Age, years | |||||
≤40 | 19 | 83.3 | 83.3 | 59.8 | 0.6749 |
41–50 | 56 | 91.1 | 78.6 | 76.8 | |
51–60 | 79 | 73.8 | 68.8 | 66.1 | |
>60 | 32 | 96.9 | 84.4 | 59.5 | |
α-fetoprotein, KIU/l | |||||
<50 | 119 | 86.6 | 81.5 | 71.2 | 0.2072 |
50–200 | 33 | 84.9 | 72.7 | 65.2 | |
>200 | 30 | 73.3 | 56.7 | 53.1 | |
Number of tumours | |||||
>3 | 11 | 72.7 | 72.7 | 32.7 | 0.0412 |
≤3 | 142 | 83.8 | 73.9 | 67.6 | |
Tumour size | |||||
>5 cm | 11 | 54.6 | 36.4 | 18.2 | 0.0002 |
≤5 cm | 131 | 87.0 | 79.4 | 72.4 | |
Milan Criteria | |||||
Within | 112 | 88.4 | 79.5 | 74.3 | 0.0164 |
Outside | 31 | 71.0 | 64.5 | 43.0 | |
UCSF Criteria (radiological) | |||||
Within | 126 | 87.3 | 78.6 | 73.1 | 0.0009 |
Outside | 17 | 64.7 | 58.8 | 27.5 | |
Pre-transplant treatment of HCC | |||||
Yes | 56 | 83.2 | 65.2 | 60.9 | 0.9736 |
No | 121 | 87.5 | 78.6 | 67.9 | |
Unknown | 9 | – | – | – | |
Era of transplant | |||||
1985–1990 | 16 | 62.5 | 50.0 | 37.4 | 0.0500 |
1991–1995 | 13 | 92.3 | 92.3 | 76.9 | |
1996–2003 | 157 | 85.4 | 77.1 | 69.3 | |
Diagnosis of HCC | |||||
Pre-LTx | 146 | 82.2 | 72.6 | 64.9 | 0.1336 |
Incidental | 38 | 89.5 | 86.8 | 74.3 |
UCSF, University of California San Francisco; HCC, hepatocellular carcinoma; LTx, liver transplantation