Table 4.
Overall survival of hepatocellular carcinoma patients after liver transplantation based on tumour characteristics
| Parameters | n |
Survival, % |
P-value | ||
|---|---|---|---|---|---|
| 1 year | 3 years | 5 years | |||
| Largest tumour diameter | |||||
| <5.0 cm | 152 | 87.0 | 81.2 | 74.4 | <0.0001 |
| ≥5.0 cm | 24 | 54.2 | 33.3 | 20.1 | |
| <6.5 cm | 161 | 85.7 | 78.3 | 71.8 | 0.0001 |
| ≥6.5 cm | 15 | 53.3 | 40.0 | 13.3 | |
| Tumour number | |||||
| >3 | 32 | 80.7 | 74.2 | 45.1 | 0.0026 |
| ≤3 | 144 | 85.4 | 76.4 | 73.0 | |
| Milan Criteria (explant) | |||||
| Within | 117 | 87.2 | 80.3 | 77.1 | 0.0002 |
| Outside | 59 | 74.6 | 62.7 | 46.1 | |
| UCSF Criteria | |||||
| Within | 132 | 86.4 | 79.6 | 76.7 | <0.0001 |
| Outside | 44 | 72.7 | 59.1 | 36.0 | |
| Capsular invasion | |||||
| Absent | 157 | 84.7 | 79.6 | 71.7 | 0.0039 |
| Present | 19 | 79.0 | 42.1 | 30.1 | |
| Vascular invasion | |||||
| None | 142 | 86.8 | 81.9 | 74.1 | <0.0001 |
| Micro | 14 | 85.7 | 64.3 | 64.3 | |
| Macro | 20 | 55.0 | 30.0 | 13.3 | |
| Lymph nodes involvement | |||||
| No | 170 | 84.3 | 76.7 | 68.3 | 0.0034 |
| Yes | 6 | 50.0 | 16.7 | 16.7 | |
| Degree of differentiation | |||||
| Well | 38 | 89.5 | 81.6 | 75.3 | 0.3854 |
| Moderate | 67 | 85.1 | 74.6 | 64.8 | |
| Poor | 21 | 81.0 | 71.4 | 71.4 | |
UCSF, University of California San Francisco