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. Author manuscript; available in PMC: 2009 Oct 1.
Published in final edited form as: Trends Cell Biol. 2008 Sep 9;18(10):456–466. doi: 10.1016/j.tcb.2008.07.009

Figure 1. Nuclear pore complex (NPC) structure and composition.

Figure 1

(a) Schematic illustration of the NPC structure (b) Predicted localization of subcomplexes and nucleoporins within the NPC. The members of the Nup214 complex (Nup214, Nup88), Nup98 complex (Nup98, Rae1), Nup107–160 complex (Nup160, Nup133, Nup107, Nup96, Nup75, Nup43, Nup37, Sec13, Seh1), Nup62 complex (Nup62, Nup58, Nup54, Nup45), and Nup93–205 complex (Nup205, Nup188, Nup155, Nup93, Nup35) are enclosed in the same box. Green lines show the location of the three transmembrane nucleoporins, red lines the location of peripheral components and blue lines indicate the location of scaffold subcomplexes.