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MSU (100 μg/ml) inhibits PDGF-mediated chemotaxis of LX-2 cells and primary mouse HSC. A: MSU inhibits PDGF-mediated chemotaxis of LX-2 HSC across a transwell with 8-μm pores (P < 0.001). B: MSU inhibits PDGF-mediated chemotaxis of primary mouse HSC across a transwell with 8-μm pores (P < 0.001). C: MSU does not inhibit PDGF-mediated chemotaxis of primary mouse HSC from ASC−/− mice across a transwell with 8-μm pores (P: NS). NS; not significant; HPF, high-power field.
