Table 1.
Total No. LP Cells | Total No. DCs | % DCs | P value | |
---|---|---|---|---|
Day 2 | ||||
Isotype | 1,945 × 103±1,088 × 103 | 159 × 103±94 × 103 | 8.7±0.4 | 0.01 |
Anti-TLR4 | 950 × 103±750 × 103 | 36 × 103±32 × 103 | 3.4±0.7 | |
Day 7 | ||||
Isotype | 4,050 × 103±600 × 103 | 463 × 103±163 × 103 | 12.3±5.8 | 0.47 |
Anti-TLR4 | 4,917 × 103±1,499 × 103 | 621 × 103±189 × 103 | 12.6±0.1 |
Data represent means ± SE of 3 mice per group. Magnetic sorting for CD11c+ cells was used to determine the number and percentage of dendritic cells (DCs) present in the total lamina propria (LP) cell population. Day 2 and day 7 correspond to the treatment schedule in Fig. 1A. P values are for % DCs in the LP.