Table 2.
Results of expression analyses by genotype
| H-W test | ANOVA | ||||||||
| Gene/Marker | Genotype |
Genotype Frequency (N) |
Allele |
Allele Frequency (N) |
χ2 value | P | F | P | |
| 5-HT2A | AA | 0.29 (4) | A | 0.46 (13) | 0.57 | 0.75 | 0.02 | 0.983 | |
| A-1438G | AG | 0.36 (5) | G | 0.54 (15) | |||||
| GG | 0.36 (5) | ||||||||
| N = 14 | |||||||||
| 5-HT2C | |||||||||
| promoter microsatellite | M | Z | 0.67 (4) | 0.02 | 0.98 | ||||
| Z-6 | 0.33 (2) | ||||||||
| F | Z-6/Z-6 | 0.14 (1) | Z-6 | 0.36 (5) | 0.84 | 0.89 | 0.14 | 0.933 | |
| Z-6/Z | 0.29 (2) | Z | 0.57 (8) | ||||||
| Z-6/Z+2 | 0.14 (1) | Z+2 | 0.07 (1) | ||||||
| Z/Z | 0.43 (3) | ||||||||
| N = 13 | |||||||||
| TPH2 | GG | 0.69 (9) | G | 0.85 (22) | 0.94 | 0.33 | 1.47 | 0.23 | |
| G-703T | GT | 0.31 (4) | T | 0.15 (4) | |||||
| N = 13 | |||||||||
| 5-HTT | SS | 0.07 (1) | S | 0.39 (11) | 0.43 | 0.81 | 0.10 | 0.91 | |
| 5-HTTLPR | SL | 0.64 (9) | L | 0.61 (17) | |||||
| LL | 0.29 (4) | ||||||||
| N = 14 | |||||||||
| 5-HTT | 10/10 | 0.09 (1) | 10 | 0.23 (5) | 0.72 | 0.70 | 0.02 | 0.98 | |
| Intron 2 VNTR | 10/12 | 0.27 (3) | 12 | 0.77 (17) | |||||
| 12/12 | 0.64 (7) | ||||||||
| N = 11 | |||||||||
Genotype frequencies, allele frequencies, results of H-W (Hardy-Weinberg) tests and ANOVA comparisons of gene expression levels (log(10) 2-ΔCt) values for the polymorphic variants are shown. Genotypes of the 5-HT2C marker are split by gender (Males = M; Females = F) since the males are hemizygotic.