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. 2009 Feb 5;24(7):2244–2251. doi: 10.1093/ndt/gfp017

Table 3.

Pharmacokinetic data

Plasma water flow rate (ml/min) 118 ± 11
Citrate plasma water clearance  (ml/min) 98 ± 10
Net citrate dose per 4 h of HD  (mmol) 17 ± 7
Citrate mass removal (%) 83 ± 5
Citrate half-life (min) 60 ± 29
Citrate distribution volume, litres  (% of body weight) 41 ± 22 (54 ± 18)
Calcium removal rate, mmol/min  (mg/min) 0.18 ± 0.02 (7.2 ± 0.8)
Calcium loss per 4 h of HD, mmol  (mg) 43 ± 4 (1720 ± 160)
Calcium substitution per 4 h of  HD, mmol (mg) 48 ± 1 (1920 ± 40)