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. Author manuscript; available in PMC: 2010 Jun 19.
Published in final edited form as: AIDS. 2009 Jun 19;23(10):1187–1195. doi: 10.1097/QAD.0b013e32832c4af0

Figure 1.

Figure 1

Effect of antiretrovirals on viral load, sensory evoked potentials, and locomotor activity (A). Plasma viral load over time, with the period of treatment indicated. Two-way ANOVA revealed a significant effect of treatment. (B) BSAEP P5 latency before infection (Preinf), after infection but before treatment (Pre-Tx), and after treatment antiretrovirals or placebo (Post-Tx). One-way ANOVA with Dunnett's post-test revealed that the placebo animals had significantly delayed latencies at the Post-Tx time point versus pre-infection (p=0.022 for the ANOVA, p<0.05 for the post-test), whereas the antiretroviral treated animals did not show a significant change. (C) Average day time locomotor activity (LCA), normalized to each animal's pre-inoculation mean, with values represent the average values during pre-infection period (Preinf), days 45 to 55 pi before treatment (Pre-Tx) and from day 87 to 95 pi after treatment (Post-Tx). One-way ANOVA did not reveal a significant change.