Fig. 4.

Progression of bronchiolitis obliterans on high resolution computed tomography in a 28-year-old woman. Bronchiolitis obliterans was diagnosed on spirometry and transbronchial lung biopsy 16 months after bone marrow transplantation for chronic myelocytic leukemia.

A. Inspiratory high resolution computed tomography scan at the time of diagnosis of bronchiolitis obliterans shows small areas of decreased lung attenuation in both upper lobes (arrows).

B. Inspiratory high resolution computed tomography scan taken nine months later at a similar anatomic level to A, shows markedly increased extent of pulmonary hypoattenuation and new development of subsegmental bronchial dilatations. The lung volume is much increased.