Table 1.
Profiles of pregnancy in the groups of dams exposed to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) or 3, 3′, 4, 4′, 5-pentachlorobiphenyl (PCB126)
| Groupsa | Number of dams | Length of pregnancy (days) | Body weight of dams (g) | Number of pups | Sex ratiob | ||
|---|---|---|---|---|---|---|---|
| Male | Female | ||||||
| Control | 7 | 21.8 ± 0.5 | 333.8 ± 17.2 | 15.4 ± 1.1 | 6.6 ± 2.0 | 8.8 ± 1.9 | 0.83 ± 0.39 |
| TCDD 50 | 8 | 21.6 ± 0.5 | 331.6 ± 21.1 | 11.0 ± 3.7 | 4.9 ± 2.1 | 6.1 ± 3.3 | 1.15 ± 0.75 |
| TCDD 200 | 6 | 21.2 ± 0.4 | 341.8 ± 31.8 | 10.8 ± 4.5 | 5.2 ± 3.5 | 5.7 ± 1.8 | 0.88 ± 0.72 |
| TCDD 800 | 6 | 21.5 ± 0.5 | 348.8 ± 25.6 | 13.0 ± 1.9 | 7.2 ± 1.6 | 5.8 ± 2.4 | 1.56 ± 1.05 |
| PCB126 500 | 8 | 21.7 ± 0.5 | 327.6 ± 44.4 | 14.3 ± 1.3 | 7.9 ± 1.5 | 6.4 ± 1.4 | 1.18 ± 0.43 |
| PCB126 2000 | 8 | 21.3 ± 0.7 | 337.0 ± 31.7 | 13.8 ± 2.1 | 7.8 ± 2.1 | 6.0 ± 1.9 | 1.19 ± 1.41 |
| PCB126 8000 | 8 | 21.4 ± 0.5 | 343.4 ± 35.6 | 14.1 ± 2.3 | 7.6 ± 1.8 | 6.5 ± 1.7 | 1.17 ± 0.34 |
Values are given as the mean ± standard error of the mean (SEM)
aPregnant Long–Evans hooded rats were administered either TCDD or PCB126 on gestational day 15. Groups of low, medium and high doses of TCDD and PCB126 were 50, 200 and 800 ng/kg of TCDD and 500, 2000 and 8,000 ng/kg of PCB126, respectively
bSex ratio is given at ♂/♀ ± standard deviation