Comparison of mRNA expression profiles of lipogenic enzymes [FAS
(░⃞), GPAT (□), ACC (░⃞), and SREBP-1a
(▧), SREBP-1c (⊡), and SREBP-2 (░⃞)]
in islets of lean (+/+) ZDF rats, untreated obese, prediabetic
(fa/fa) ZDF rats, or obese,
prediabetic (fa/fa) ZDF rats
treated with TGZ. (*, P < 0.0005; ¶,
P < 0.05 lean +/+ vs. obese
fa/fa; §, P <
0.005; #, P < 0.05 obese
fa/fa vs. obese
fa/fa with TGZ.)