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(A) Effect of adenoviral induction of hyperleptinemia on hepatic expression of SREBP-1 (■) and the lipogenic enzymes FAS (░⃞), GPAT (□), and ACC (░⃞). Data were normalized by 18S RNA. (B) Semiquantification of SREBP-1a (▧), -1c (⊡), and -2 (░⃞) by RT-PCR. (*, P < 0.005; §, P < 0.05 AdCMV-β-gal vs. AdCMV-leptin.)
