TABLE 3.
Antimicrobial activities of recombinant and synthetic BIIb
| Microorganism | MIC (μg/ml)a
|
|
|---|---|---|
| Recombinant BIIb | Synthetic BIIb | |
| Gram-positive bacteria | ||
| Bacillus subtilis | 2 | 2 |
| Staphylococcus aureus | 0.5 | 0.5 |
| Streptococcus mutans | 2 | 2 |
| Gram-negative bacteria | ||
| Escherichia coli | 2 | 2 |
| Pseudomonas putida | 2 | 2 |
| Salmonella enterica serovar Enteritidis | 1 | 1 |
| Fungi | ||
| Cryptococcus neoformans | 2 | 2 |
| Saccharomyces cerevisiae | 2 | 2 |
| Candida albicans | 1 | 1 |
a
The MIC represents the amount of AMP required to inhibit growth of the microorganism. Each MIC was determined from two independent experiments performed in triplicate.