TABLE 1.

Comparative statistics for enzymes and metabolites that were used for the metabolic reconstructions of 13 S. aureus strains^a

Parameter	No. for strain:
	Newman	TCH1516	USA300	Mu3	JH9	JH1	COL	RF122	Mu50	MW2	MSSA476	MRSA252	N315
ORFs	2,641	2,683	2,604	2,698	2,726	2,681	2,618	2,515	2,714	2,632	2,597	2,655	2,593
ORFs with functions	1,915	1,896	2,002	2,031	2,087	2,096	1,953	1,915	2,091	2,021	1,975	2,024	2,031
unique full EC no.	650	646	671	663	670	663	666	666	667	665	671	675	668
Dual-fusion enzymes	51	49	50	51	51	51	50	50	50	50	49	49	51
Triple-fusion enzymes	6	6	6	6	6	6	6	6	6	6	6	6	6
Quadruple-fusion enzymes	4	4	4	4	4	4	4	4	4	4	4	4	4
Very likely reactions	1,231	1,213	1,255	1,247	1,254	1,247	1,254	1,248	1,251	1,251	1,258	1,258	1,253
Less likely reactions	215	220	218	218	220	219	214	225	219	215	216	221	220
Likely reactions	20	19	20	20	20	19	20	16	20	20	20	20	20
EC no. with reactions	534	522	544	543	547	541	538	537	545	540	540	544	546
Cellular reactions	1,208	1,186	1,224	1,222	1,227	1,220	1,214	1,213	1,225	1,219	1,217	1,223	1,227
Transport reactions	141	146	148	144	146	145	150	151	145	147	152	152	146
Exchange reactions	117	120	121	119	121	120	124	125	120	120	125	125	120
Metabolites	1,412	1,399	1,428	1,422	1,431	1,422	1,425	1,414	1,427	1,421	1,432	1,437	1,431

^aThe numbers of ORFs, functions, cellular reaction metabolites, and transport reactions identified for all the strains were used in the FBA and synthetic-lethal studies.