TABLE 8.
Function | Locus tag | Gene | Fold expression
|
P | |
---|---|---|---|---|---|
Pre-diamide stress | 90 min PDS | ||||
Virulence | Rv3667 | hbhA | 1.203 ± 0.010 | 0.502 ± 0.185 | 0.051 |
Lipid metabolism | Rv3825c | pks2 | 2.535 ± 0.003 | 0.550 ± 0.320 | 0.037 |
Hypothetical proteins | MT1775 | 1.283 ± 0.003 | 0.339 ± 0.117 | 0.031 |
The functional categorization of M. tuberculosis genes was based on their known functions as assigned by the TubercuList database (http://genolist.pasteur.fr/TubercuList/). For each gene, the changes in wild-type M. tuberculosis relative to the levels for the Δ-σH mutant in the pre-diamide stress samples and the 90-min-PDS samples are shown, along with standard deviations. Statistical significance was assigned using the ANOVA function within the S+ ArrayAnalyzer script.