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Regulation of exopolysaccharide synthesis machinery by c-di-GMP. Binding of c-di-GMP to both hypothesized and known components of the exopolysaccharide synthesis machinery has been shown for cellulose synthase (A), the PEL synthesis complex (B), and alginate synthetase (C). Activation of these enzymes by c-di-GMP could be a common mechanism of regulating exopolysaccharide synthesis by this second messenger.
