Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Analysis of inactivation of the wt Apc allele as a function of Muc2 gene dosage
| Mutation − LOH + | Mutation + LOH − | Mutation+ LOH + | Mutation − LOH − | |
|---|---|---|---|---|
| LOH | 10 | 5 | ||
| Muc2+/−Apc1638N/+ (n =20) | 5 | 8 | 4 | 3 |
| Muc2−/−Apc1638N/+ (n = 22) | 5 | 3 | 1 | 13 |
n = number of tumors analyzed
