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Comparison of the productivities of SEAP-producing CHO cells under three different culture conditions in biphasic culture mode. Accumulated activity of SEAP in different culture conditions. [suspension (▲), Cytodex 3 (▼), Cytopore 1(■)]. Vertical dashed arrows at 95 and 133 h indicate the time of temperature reduction from 37 °C to 33 °C for suspension and microcarrier cultures, respectively
