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Effects of capsaicin (CAP) given via left renal pelvis perfusion (LRPP) on filtered sodium load (FLNa), distal delivery of sodium (DDNa) and distal sodium reabsorption (DRNa). CAP significantly increased FLNa (A), DDNa (B) and DRNa (C) by activation of the TRPV1 in the renal pelvis and these effects were abolished by blockade of the TRPV1 with capsazepine (CAPZ) (n= 5–6 rats). ++ p < 0.01 vs Vehicle, CAPZ + CAP, and CAPZ groups.
