Table 3.
Pharmacokinetic parameters of immunotoxins
| t1/2, min | MRT, min | AUC, ng⋅min/ml | |
|---|---|---|---|
| LMB-2 | 13 | 34.1 | 31,604 |
| Mutant LMB-2 | 13 | 35.3 | 31,385 |
| PEG5k-LMB-2 | 66 | 67.9 | 111,589 |
| PEG20k-LMB-2 | 106 | 75.3 | 145,835 |
Values are calculated from data in Fig. 5.
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