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. 2009 Apr 22;83(13):6610–6623. doi: 10.1128/JVI.02655-08

TABLE 2.

Interactions described in this study

Nucleoporin NPC localizationa Motifb Resultf
HSV-1 capsid IPc HSV-1 pUL25 IPc PrV pUL25 yeastd
CAN/Nup214e Cyto FG, Gly, CC, BP, LZ, AH + + +
hNup153 Nuc FG, Gly, ZF NT NT
hNup133 Cyto + Nuc BP, AHR NT
hNup54 Cyto + Nuc FG, Gly, CC NT
hNup50 Nuc FG, RBD NT
hCG1 Cyto FG, ZF, CC + +g
POM121 PM FG, Gly, TM NT NT
Nup98 Nuc FG, Gly NT NT
a

Cyto, cytoplasmic face; Nuc, nucleoplasmic face; PM, pore membrane (11).

b

FG, FG repeats; Gly, glycosylated; RBD, Ran-binding domain; ZF, zinc fingers; CC, coiled coil; LZ, leucine zipper; AH, amphipathic helix; BD, β-propeller; TM, transmembrane helix.

c

IP, immunoprecipitation. See Fig. 1 and 2 for details.

d

See Table 3 for details.

e

Only amino acids 1594 to 2090 (see Fig. 1 and 2 and Table 3 for details).

f

NT, not tested.

g

Only amino acids 1 to 380 (see Table 3 for details).