FIG. 9.

Organization of HRSV M2-1. (A) Sequence alignment of HRSV, BRSV, mouse pneumovirus (MPV), human metapneumovirus (HMPV), and avian metapneumovirus (AMPV) M2-1 proteins by ClustalW. Acidic residues are in red, basic residues are in blue, hydrophobic residues are in green, and glycines are in boldface. Asterisks and colons indicate identities and homologies, respectively. (B) Hydrophobic cluster analysis plot for HRSV M2-1. Structured regions are characterized by a high number of hydrophobic clusters, while unstructured regions have low numbers or are devoid of hydrophobic clusters. Secondary structure predictions were performed with PSI-PRED (21) and are shown below the plot.