TABLE 1.
Treatment (no. of PFU) | 129SvEv
|
C57BL/6
|
||||||||
---|---|---|---|---|---|---|---|---|---|---|
Frequency positive | No. positive/total
|
P valuea | Frequency positive | No. positive/total
|
P valuea | |||||
Score 1 | Score 2 | Both | Score 1 | Score 2 | Both | |||||
Mock infection | 0.15 | 9/62 | 0/62 | 9/62 | 0.20 | 5/25 | 0/25 | 5/25 | ||
102 | 0.37 | 11/30 | 0/30 | 11/30 | 0.016 | NDb | ND | ND | ND | ND |
103 | 0.57 | 17/30 | 0/30 | 17/30 | <0.0001 | ND | ND | ND | ND | ND |
104 | 0.68 | 22/38 | 4/38 | 26/38 | <0.0001 | 0.80 | 19/25 | 1/25 | 20/25 | <0.0001 |
107 | 0.69 | 9/16 | 2/16 | 11/16 | <0.0001 | 0.90 | 8/10 | 1/10 | 9/10 | <0.0001 |
P values were determined by unpaired two-tailed t tests comparing the raw diarrheal scores of infected groups to those of mock-infected controls.
ND, not done.